On October 23, 2017 the Stimson Center, United States Department of State, and Michigan State University co-hosted a workshop on leveraging geospatially-enabled information to combat wildlife trafficking, one of the largest illicit markets in the world. The workshop was designed to bring together non-governmental (NGO), U.S. Government (USG), and academic experts to enhance database standards for wildlife trafficking geoinformatics, including identifying types of geographic information that would help end-users be more effective in combating wildlife trafficking, key common denominators for geospatial information databases in transboundary contexts, and coping with conditions of data delivery. The intent was to adapt insights from this workshop to future regional workshops in southern and central Africa for practitioners working to combat wildlife trafficking in both a national and transboundary context. Approximately 55 individuals representing 11 NGOs, 4 universities, 6 federal agencies, 1 development bank, 2 private sector organizations, and 1 professional scientific society participated in the workshop. Three discussion-based panels were followed by an interactive exchange.